We study deep neural networks and their use in semiparametric inference. We establish novel nonasymptotic high probability bounds for deep feedforward neural nets. These deliver rates of convergence that are sufficiently fast (in some cases minimax optimal) to allow us to establish valid second‐step inference after first‐step estimation with deep learning, a result also new to the literature. Our nonasymptotic high probability bounds, and the subsequent semiparametric inference, treat the current standard architecture: fully connected feedforward neural networks (multilayer perceptrons), with the now‐common rectified linear unit activation function, unbounded weights, and a depth explicitly diverging with the sample size. We discuss other architectures as well, including fixed‐width, very deep networks. We establish the nonasymptotic bounds for these deep nets for a general class of nonparametric regression‐type loss functions, which includes as special cases least squares, logistic regression, and other generalized linear models. We then apply our theory to develop semiparametric inference, focusing on causal parameters for concreteness, and demonstrate the effectiveness of deep learning with an empirical application to direct mail marketing.

We study regression discontinuity designs when covariates are included in the estimation. We examine local polynomial estimators that include discrete or continuous covariates in an additive separable way, but without imposing any parametric restrictions on the underlying population regression functions. We recommend a covariate-adjustment approach that retains consistency under intuitive conditions and characterize the potential for estimation and inference improvements. We also present new covariate-adjusted mean-squared error expansions and robust bias-corrected inference procedures, with heteroskedasticity-consistent and cluster-robust standard errors. We provide an empirical illustration and an extensive simulation study. All methods are implemented in R and Stata software packages.

Portfolio sorting is ubiquitous in the empirical finance literature, where it has been widely used to identify pricing anomalies. Despite its popularity, little attention has been paid to the statistical properties of the procedure. We develop a general framework for portfolio sorting by casting it as a nonparametric estimator. We present valid asymptotic inference methods and a valid mean square error expansion of the estimator leading to an optimal choice for the number of portfolios. In practical settings, the optimal choice may be much larger than the standard choices of five or ten. To illustrate the relevance of our results, we revisit the size and momentum anomalies.

Binscatter is a popular method for visualizing bivariate relationships and conducting informal specification testing. We study the properties of this method formally and develop enhanced visualization and econometric binscatter tools. These include estimating conditional means with optimal binning and quantifying uncertainty. We also highlight a methodological problem related to covariate adjustment that can yield incorrect conclusions. We revisit two applications using our methodology and find substantially different results relative to those obtained using prior informal binscatter methods. General purpose software in Python, R, and Stata is provided. Our technical work is of independent interest for the nonparametric partition-based estimation literature. (JEL C13, C14, C18, C51, O31, R32)