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Trade Specialisation, Technology and Economic Growth. Theory and Evidence from Advanced Countries
The Management of Technological Innovation
The Economic Challenge for Europe: Adapting to Innovation Based Growth
Governing Molecules. The Discoursive Politics of Genetic Engineering in Europe and the United States
Knowledge and Investment: The Sources of Innovation in Industry
The Cambridge Phenomenon Revisited: Parts One and Two
Research across the social and primary health care interface: methodological issues and problems
Juvenile gigantomastia in a 12-year-old girl was treated by a bilateral reduction mammoplasty with free transplantation of the areolae and nipples and the removal of 3,980 g of breast tissue. Regrowth of the residual breast tissue has been suppressed by the administration of tamoxifen, an antiestrogen drug, since the surgery. This case was positive for estrogen receptors (ER) by the dextran-coated charcoal method, while tissue staining for ER and estradiol resulted in a darker staining of the epithelial contents, especially of fibroadenoma-like nodules, using an immunocytochemical assay. It is thus suggested that the etiology of this disease might be related to a local hypersensitivity to estrogen.