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Review of Economic Studies Vol. 86 No. 1 2019

Public R&D Investments and Private-sector Patenting: Evidence from NIH Funding Rules

Pierre Azoulay1; Joshua S. Graff Zivin2; Danielle Li1; Bhaven N. Sampat3

1 MIT and NBER · 2 UCSD and NBER · 3 Columbia University and NBER

open access

Abstract

We quantify the impact of scientific grant funding at the National Institutes of Health (NIH) on patenting by pharmaceutical and biotechnology firms. Our paper makes two contributions. First, we use newly constructed bibliometric data to develop a method for flexibly linking specific grant expenditures to private-sector innovations. Second, we take advantage of idiosyncratic rigidities in the rules governing NIH peer review to generate exogenous variation in funding across research areas. Our results show that NIH funding spurs the development of private-sector patents: a $10 million boost in NIH funding leads to a net increase of 2.3 patents. Though valuing patents is difficult, we report a range of estimates for the private value of these patents using different approaches.

DOI
10.1093/restud/rdy034
Volume
86
Issue
1
Pages
117-152
Language
en
Sources
openalex crossref bibtex:phds-export.bib

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