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The Review of Economics and Statistics Vol. 108 No. 3 2026

Improving Estimation Efficiency via Regression-Adjustment in Covariate-Adaptive Randomizations with Imperfect Compliance

Liang Jiang1; Oliver B. Linton2; Haihan Tang1; Yichong Zhang3

1 International School of Finance Fudan University · 2 University of Cambridge · 3 Singapore Management University

Abstract

We investigate how to improve efficiency using regression adjustments with covariates in covariate-adaptive randomizations (CARs) with imperfect subject compliance. Our regression-adjusted estimators, which are based on the doubly robust moment for local average treatment effects, are consistent and asymptotically normal even with heterogeneous probabilities of assignment and misspecified regression adjustments. We propose an optimal but potentially misspecified linear adjustment and its further improvement via a nonlinear adjustment, both of which lead to more efficient estimators than the one without adjustments. We also provide conditions for nonparametric and regularized adjustments to achieve the semiparametric efficiency bound under CARs.

DOI
10.1162/rest_a_01417
Volume
108
Issue
3
Pages
774-791
Language
en
Sources
openalex crossref

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